Alternative Names
Renal tubular acidosis - proximal; Type II RTA; RTA - proximal; Renal tubular acidosis type II
Definition of Proximal renal tubular acidosis:
Proximal renal tubular acidosis is a condition that occurs when the kidneys don't properly remove acids in the urine, leaving the blood too acidic.Causes, incidence, and risk factors:
Your kidneys help regulate your body's acid-base balance (pH). Acidic substances in the body are buffered (counteracted) by alkaline substances, primarily bicarbonate.
The kidneys contain more than a million filtering units, called nephrons. Bicarbonate is reabsorbed into the blood in the nearest (proximal) tubule of each nephron. Proximal renal tubular acidosis (Type II RTA) occurs when bicarbonate isn't properly reabsorbed by the proximal tubules, leaving the body in an acidic state (called acidosis).
Type II RTA is less common than Type I RTA. It most often occurs during infancy, and may go away by itself.
Causes of type II RTA include:
