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Atrophic vaginitis - Overview

Alternative Names

Vaginitis - atrophic; Vaginitis due to reduced estrogen

Definition of Atrophic vaginitis:

Atrophic vaginitis is inflammation of the vagina due to thinning tissue and decreased lubrication. It is related to reduced estrogen levels.

For other types and causes of vaginitis, see: Vulvovaginitis

Causes, incidence, and risk factors:

Atrophic vaginitis is caused by a decrease in estrogen. Estrogen levels normally drop after menopause.

Estrogen is very important in keeping the tissues of the vagina lubricated and healthy. Normally, the lining of the vagina makes a clear, lubricating fluid. This fluid makes sexual intercourse more comfortable and helps decrease vaginal irritation.Thinning or shrinking of the vaginal tissue causes dryness and inflammation.

The following may cause estrogen levels to drop and lead to atrophic vaginitis:

  • Medications or hormones used to decrease estrogen levels in women, as part of the treatment for breast cancer, endometriosis, fibroids, or infertility
  • Radiation treatment to the pelvic area or chemotherapy
  • Severe stress, depression, or rigorous exercise

Atrophic vaginitis may occur in younger women who have had surgery to remove their ovaries. Some women develop the condition immediately after childbirth or while breastfeeding, since estrogen levels are lower at these times.

The vagina can also become further irritated from soaps, laundry detergents, lotions, perfumes, or douches. Certain medications, smoking, tampons, and condoms may also cause or worsen vaginal dryness. For more information on these causes of vaginitis, see: vulvovaginitis.

  • Reviewed last on: 12/9/2009
  • Linda Vorvick, MD, Seattle Site Coordinator, Lecturer, Pathophysiology, MEDEX Northwest Division of Physician Assistant Studies, University of Washington School of Medicine; and Susan Storck, MD, FACOG, Chief, Eastside Department of Obstetrics and Gynecology, Group Health Cooperative of Puget Sound, Redmond, Washington; Clinical Teaching Faculty, Department of Obstetrics and Gynecology, University of Washington School of Medicine. Also reviewed by David Zieve, MD, MHA, Medical Director, A.D.A.M., Inc.

References

Eckert LO, Lentz GM. Infections of the lower genital tract: vulva, vagina, cervix, toxic shock syndrome, HIV infections. In: Katz VL, Lentz GM, Lobo RA, Gershenson DM, eds. Comprehensive Gynecology. 5th ed. Philadelphia, Pa: Mosby Elsevier; 2007:chap 22.

Lobo RA. Menopause: endocrinology, consequences of estrogen deficiency, effects of hormone replacement therapy, treatment regimens. In: Katz VL, Lentz GM, Lobo RA, Gershenson DM, eds. Comprehensive Gynecology. 5th ed. Philadelphia, Pa: Mosby Elsevier; 2007:chap 42.

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