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Gangrene - Overview

Definition of Gangrene:

Gangrene is the death of tissue in part of the body.

Causes, incidence, and risk factors:

Gangrene happens when a body part loses its blood supply. This may happen from injury, an infection, or other causes. You have a higher risk for gangrene if you have:

  • A serious injury
  • Blood vessel disease (such as arteriosclerosis, also called hardening of the arteries, in your arms or legs)
  • Diabetes
  • Suppressed immune system (for example, from HIV or chemotherapy)
  • Surgery
  • Reviewed last on: 5/19/2008
  • Sean O. Sitham, MD, private practice in Internal Medicine, Seattle, WA; Jatin M. Vyas, MD, Instructor in Medicine, Harvard Medical School, Assistant in Medicine, Division of Infectious Disease, Massachusetts General Hospital. Review provided by VeriMed Healthcare Network. Also reviewed by David Zieve, MD, MHA, Medical Director, A.D.A.M., Inc.

References

Meislin HW, Guisto JA. Soft Tissue Infections. In: Marx, JA, ed. Rosen's Emergency Medicine: Concepts and Clinical Practice. 6th ed. Philadelphia, PA: Mosby Elsevier; 2006: chap 135